Celandine is a great botanical description. The use of celandine in folk medicine for the treatment of skin diseases, in gynecology. Preparation of preparations from celandine

Chelidonium majus L.
Taxon: Poppy family (Papaveraceae)
Popular names: warthog, cleaver, yellow milkman, swallow grass, light grass.
English: Greater celandine

Description:
Greater celandine is a perennial herbaceous plant 30-100 cm high, containing orange milky juice in all parts. The stem is covered with sparse hairs, ribbed, erect, hollow. The leaves of the plant are feathery, alternate, gray-gray below, light green above, sessile upper leaves, lower ones on long petioles. The flowers sit on long stalks, bloom in May - June, they are bright yellow, and are collected in umbrellas at the ends of the stems. The fruit ripens in July - September in the form of a pod-shaped unilocular capsule. Seeds are shiny, dark brown, ovoid.
Greater celandine is widespread in Siberia, in the European part of Russia, in Central Asia, in the Far East. Celandine grows along roads, near houses, in gardens, in vegetable gardens as a weed plant.

Collection and procurement:
The herb of celandine is used as the main medicinal raw material. It is harvested during flowering, cutting with knives or sickles, and when standing densely, flowering tops without rough lower parts are mowed with braids. To preserve the thickets, re-harvesting in the same place should be carried out no earlier than a year later. Due to the toxicity of the plant, during the collection of raw materials, you should not touch your face or eyes with your hands; wash your hands thoroughly after work. Collecting raw materials celandine can only be carried out in dry weather. Dried without delay in dryers at a temperature of heating the raw material to 50-60 ° C, in attics under an iron, tile or slate roof or under sheds with good ventilation, spreading it loosely in a thin layer, periodically turning it over. On slow drying and in those cases when it is decomposed in a thick layer, it turns brown and rots. Raw materials are considered dry if the stems break when bent rather than bent. The shelf life of raw materials is 3 years. The smell of raw materials is peculiar, the taste is bitter. The main procurement areas are in Ukraine and Russia.
Rhizomes with roots are harvested in early spring, at the beginning of the growth of the aerial part, or in the fall - after it dies off. Having dug up with shovels, they shake off the ground and cut off the stems.
Then immediately wash them in cold water.

Chemical composition:
All organs of the celandine plant contain complex alkaloids (in the grass up to 2%, in the roots up to 4%) -stilopin, protopin, chelidonin, homohelidonin, berberine, spartein, helidamine, etc.; carotene (up to 14.9 mg%), ascorbic (up to 170 mg%), chelidonic, chelidonic, malic, citric and succinic acids, saponins, flavonoids, essential oil (0.01%); the seeds contain fatty oil (40-60%), coumarins, and the milky juice contains resinous substances.
The celandine herb contains: ash - 15.01%; macroelements (mg / g): K - 58.20, Ca - 27.20, Mn - 4.30, Fe - 0.60; trace elements (CBN): Mg - 0.16, Cu - 1.34, Zn - 1.16, Co - 0.31, Mo - 12.50, St - 0.33, Al - 0.25, Ba - 2 , 48, V - 0.20, Se - 12.50, Ni - 0.35, Sr - 0.49, Pb - 0.14, I - 0.08, Br - 111.60, Ag - 8.00 ... B -55.00 μg / g. Cd, Li, Au were not found. Concentrates Cu, Zn, Mo, Ba, Se, Ag, Fe, Br. Can accumulate Mn, Co. s.

Pharmacological properties:
Celandine has antispasmodic, sedative effects, affects the secretion of bile and its excretion into the intestines, and also has pronounced antiviral and antibacterial properties.
The celandine plant inhibits the growth of malignant tumors, has a fungistatic and bacteriostatic effect against tubercle bacillus, enhances intestinal peristalsis and saliva secretion, reduces the reactivity of vegetative nervous system, tones up the smooth muscles of the uterus.

Application in medicine:
Rhizomes, roots. Decoction- v folk medicine with dysentery.
Roots are part of the drugs prescribed for cholelithiasis, relapses of hepatitis, cholecystitis.
Roots, aerial part. Decoction- in folk medicine for rheumatism, hypertension, dysentery.
Aboveground part... It is a part of complex preparations "Enterosanal" and "Plantazan B" (ointment for the treatment of warts). The latter is approved for use in the treatment of cutaneous tuberculosis. Used in homeopathy.
Tincture, juice, a mushy mass was used for cauterization of warts, genital warts, for psoriasis, eczema, lupus erythematosus, for the treatment of laryngeal papillomatosis in children, periodontal disease, colon polyposis, rectal polyps, for diseases of the liver, gallbladder and ducts.
In folk medicine of different countries, juice, decoctions, baths, powder are widely used for various skin diseases: skin and lip cancer, fungal diseases, eczema, condylomas, urticaria, erysipelas, corns, ulcers, psoriasis, scabies, burns, boils, warts, freckles.
Juice- for the treatment of trachoma, thorns, diseases of the stomach, liver and gallbladder; has an antispasmodic and diuretic effect. In homeopathy - for diseases of the liver and bile ducts.
Leaves. Used to cover infected wounds.
Flowers. In Tibetan medicine - as an antipyretic.

The use of a medicinal plant celandine large:
Greater celandine is used in the treatment of disorders of the liver, intestines, gallbladder.
Fresh juice and decoction of celandine herb inhibit the growth of malignant tumors, have a bacteriostatic effect on mycobacterium tuberculosis. The sap of the plant is used in the treatment of chronic prostatitis.
The infusion of celandine is used in the treatment of certain skin diseases and gout. An infusion of great celandine herb is drunk with atherosclerosis.
The fresh juice of the celandine plant is used to treat acne, calluses and warts are burned with it. It is used for fungal diseases, scabies, breast tumors, eczema.
Children are bathed in a decoction of celandine for various skin diseases, its use helps with itchy dermatoses. In addition, celandine is a good treatment for burns and frostbite.

Plant medicinal products:
Infusion of celandine herb (Infusum herbae Chelidonii majoris)
Infusion as a choleretic, laxative and remedy.
1 tbsp. pour a spoonful of celandine herb with a quarter liter of boiled hot water, then heat in a water bath for a quarter of an hour, cool for an hour, filter. Bring the volume of the infusion boiled water up to 250 ml. Drink half a glass a quarter of an hour before meals 2-3 times a day.
Infusion for biliary dyskinesia.
2 tbsp. tablespoons of celandine herb pour half a liter of boiled water, leave for 4 hours, then strain. Take 3/4 cup in the evening and in the morning on an empty stomach at a time.
Infusion for atherosclerosis.
Brew a tablespoon of chopped celandine herb with a glass of boiling water, leave for half an hour, strain. Drink 0.5 cups three times a day.
Tincture of celandine.
Pour 20 g of celandine herb with a glass of vodka, leave for 10 days, shaking occasionally, filter, squeeze out the used raw materials. Drink 25 drops for shortness of breath.
Infusion for sweating feet.
200 g of celandine herb, brew 2 liters of boiling water, leave the herb until it cools. Soak your feet.
Decoction of celandine herb (Decoctum herbae Chelidonii majoris)
5 g of raw materials are poured into 200 ml of boiling water, boiled for 10 minutes, infused for 20 minutes, then filtered. Take 1-2 tablespoons 3 times daily before meals.
Celandine juice.
Fresh grass with roots is washed, put in the shade to dry out from the water. Then it and the roots are scrolled through a juicer or meat grinder. The resulting mass is wrung out. The juice is poured into a dark glass bottle so that 1-2 cm remains to the edge of its neck and tightly closed. Every day, air is released from the bottle until it stops coming out. The juice should be amber. Store the bottle in a cool, dark place, but not in the refrigerator.
Celandine juice is instilled into the nose in 1-2 drops for sinusitis, warts are reduced to them, sore spots are lubricated during the deposition of salts, the gums are lubricated in case of their disease 3-5 times with an interval of 3-4 minutes.
For growth, strengthening and strengthening of hair, the juice is diluted with water in a ratio of 1: 2 and rubbed into the hair roots.

Contraindications:
The medicinal plant celandine large contains toxic substances. It cannot be dried in a room where people sleep.
You can take celandine products only under the supervision of a doctor. It can cause poisoning, fainting, hallucinations, seizures, and central nervous system paralysis. Contraindicated in pregnant women, patients with chronic heart ischemia, bronchial asthma, epilepsy, hypertensive patients. With excessive topical application, celandine juice can cause inflammation of the skin, usually with the formation of blisters.

Phytopreparations containing celandine

1. Herb celandine - Herba Chelidonii
Produced in boxes of 50 and 100 g. One tablespoon of raw materials is poured into an enamel bowl, 200 ml (1 glass) of boiling water is poured, covered with a lid and infused in a water bath for 15 minutes, and then cooled at room temperature within 45 minutes. and filter. The remaining raw materials are squeezed out. The volume of the resulting infusion is brought to 200 ml with boiled water. The prepared infusion is stored in a cool place for no more than 2 days. Take 1 / 2-1 / 3 glasses 2-3 times a day for 15 minutes. before meals as a diuretic, laxative and remedy.

2. Celandine elixir
An external product containing celandine elixir. Available in ampoules of 1, 2 ml. Highly effective product. Method of application: apply 1 drop of the drug to a wart, dry corn or papilloma and leave for a while until the liquid is completely absorbed.
With papilloma, 1 drop of the drug is applied once a day, with warts - 1 drop a day for 3 days, with calluses - 1 drop a day for 5 days.
When using the drug, you need to be careful and make sure that the liquid does not get on healthy areas of the skin and the mucous membrane of the lips and eyes. It is strictly forbidden to use a product for removing moles and birthmarks.

3. Vitaon
An oil solution containing oil extracts of peppermint leaves ( Mentha piperita), chamomile flowers ( Matricaria recutita), large celandine herbs ( Celidonium majus), herb wormwood ( Artemisia absinthium), Scots pine buds ( Pinus silvestris), fruits of common fennel ( Foeniculum vulgare), fruits of May rosehip ( Rosa majalis), fruits of common caraway ( Carum carvi), herb yarrow ( Achillea millefolium), herbs creeping thyme ( Thymus serpyllum), herbs Hypericum perforatum ( Hypericum perforatum), flowers of calendula officinalis ( Calendula officinalis), camphor, peppermint essential oil ( Mentha piperita) and essential oil of fennel ordinary ( Foeniculum vulgare).
It is used as a regenerating, wound-healing, analgesic, anti-inflammatory and antimicrobial agent for injuries and lesions of the skin and mucous membranes in dermatology, for burns (thermal, chemical, solar) of I – III degrees, respiratory infections. Increases the body's resistance to harmful environmental factors (radiation, thermal, chemical, mechanical action). Apply externally. A gauze bandage is moistened with a product and applied to the wound every 2-3 days or applied to the wound surface with a thin layer (0.1–0.5 ml per 100 cm of the affected area), repeating the procedure 2 times a day.
Release form: bottles of 25, 30, 50 and 500 ml.

4. Agrimonas N (Niedermaler, Germany)
It is produced in bottles in the form of a solution, 100 ml of which contains 72 ml of an extract made by percolation from 3.3 g of dandelion roots and leaves; 3 g of celandine herb; 4.4 g of wormwood herb. Used for dyspepsia and other functional disorders of activity gastrointestinal tract... Consume 1 tablespoon 3 times a day.

5. Arіstochol Koncentrat (Steiner, Germany)
Available in capsules and granules. 1 capsule contains 15-25 mg of dry extract of celandine herb, 1.65-2.5 mg of turmeric root extract, 100-125 mg of dry extract of Cape Aloe. Used for dyspeptic disorders, especially for functional disorders of the digestive system

6. Ardeycholan N (Ardeypharm, Germany)
Dragee containing 300 mg of dry extract of celandine. It is used for mild spastic disorders in the gastrointestinal tract and gallbladder. It is used for acute diseases of the biliary tract, with the exception of obstruction, for violations after hepatitis and pancreatic secretion, as well as for constipation.

7. Aristochol N (Steiner, Germany)
Drops, 100 ml of which contain a mixture of tinctures made in a ratio of 1: 7 per 547 ml of alcohol: from celandine herb 20 mg in terms of chelidonine; from senna leaves 17 ml; dandelion herbs and roots 17 ml; herbs bitter wormwood 15 ml. It is used for digestive disorders, especially after a meal, for disorders of pancreatic secretion, for cholecystopathy and biliary dyskinesia.

8. Bilisan C 3 (Repha, Germany)
Film-coated tablets containing 100 mg of dry extract of celandine, standardized by the amount of alkaloids in terms of nachelidonine, 85 mg of dry milk thistle extract and 25 ml of dry extract of crushed turmeric roots. It is used for chronic hepatitis and cirrhosis of the liver, cholelithiasis, cholangitis, biliary dyskinesia, accompanied by dyspeptic disorders.

9. Bomagall forte S (Hevert, Germany)
Drops containing a mixture of liquid extracts (1: 1) made from celandine herb 67 ml, shepherd's purse herb 8.3 ml, milk thistle seeds 2.2 ml, Pallida echinacea roots 2.5 ml; in combination with 5 homeopathic remedies from carrot-like visnaga, atropine sulfate, milk thistle, echinacea and dandelion. It is used for pain accompanying diseases of the liver and biliary tract, and for hepatogenic constipation.

10. Cefachol N (Cefak, Germany)
Drops, 100 ml of which contain alcoholic extracts (1: 5), made from 30 g of celandine herb, 30 g of milk thistle fruit, 40 g of dandelion leaves and roots. It is used for insignificant biliary tract disorders. Used for maintenance therapy of chronic inflammatory liver diseases.
11. Chelidophyt (Galenica Hetterich, Germany)
Dragee containing 200 mg of dry extract of celandine, made in a ratio of 5-10: 1, which contains 20 mg of alkaloids in terms of chelidonine. Used for obturation of the biliary tract.

12. Chelidonium-Strath (Strath-Labor, Germany)
Drops containing 100 ml of total aqueous-alcoholic extract (1:25) from 2 g of celandine herb, 0.8 g of agine grass, 0.6 g of sage leaves and 0.6 g of St. John's wort. Used for cholecystopathy, biliary dyskinesia and hepatopathy.

13.Cholagogum F Natterman (Natterman, Germany)
Capsules containing dry extract of celandine (5–10: 1) 104 mg, which contains 4 mg of alkaloids in terms of chelidonine and dry extract of turmeric (12.5–25: 1) 45 mg. It is used for mild stomach cramps caused by functional disorders of the biliary tract.

14.Cholagogum N Natterrman (Natterman, Germany)
Drops, 100 ml of which contain the amount of liquid alcohol extracts (1: 2), in particular 20 ml of extract from 2.5 g of celandine herb and 20 ml of extract from 7.5 g of turmeric rhizomes 0.18 ml, peppermint essential oil. Used for cholecystopathies and chronic cholangitis, cholelithiasis and biliary dyskinesia.

15. Chol-4000 Lichtenstein (Lichtenstein, Germany)
Film-coated tablets that contain 200 mg of dry extract of celandine, standardized by the amount of alkaloids 2.1%. Used for mild spasms of the biliary tract and gastrointestinal tract.

16. Cholagutt N (Albert-Roussel, France)
Drops containing a tincture of a mixture of celandine, lavender and peppermint. They are used for acute and chronic diseases of the biliary tract and gallbladder, dyskinesia and cholelithiasis.

17. Cholapret forte (Bioronica, Germany)
Film-coated tablets and drops. The tablets contain 152 mg of boldo leaf dry extracts, 180 mg of celandine herb. 100 ml drops contain a liquid extract made from 22.8 g of boldo leaves, 63 g of celandine herb and 9.3 g of turmeric rhizomes. It is used for severe spasms of the biliary tract, gastrointestinal tract and dyspeptic disorders.

18. Cholarist (Steiner, Germany)
Tablets containing 100-150 mg of celandine herb dry extract (5-7: 1). It is used for spasms of the biliary tract and in the area of the gastrointestinal tract.

19. Cholhepan (Schuck, Germany)
Dragee containing dry extract of celandine herb 15 mg, milk thistle leaves 30 mg and aloe leaves 40 mg. It is used as a choleretic and antispasmodic agent for constipation.

20. Choledoron (Weleda, Germany)
Drops containing ethanol extract (1: 1.8) from celandine rhizomes 2.5 g and ethanol decoction 1:10 of turmeric rhizomes. It is used as a choleretic agent for liver diseases with impaired bile secretion.

21. Choll-Kugeletten Neu (Dolorgiet, Germany)
Dragee containing dry extracts of celandine 50 mg and aloe 50 mg. It is used for mild spasms of the biliary tract with unwanted easy defecation.

22. Cholosom-Phyto (Hevert, Germany)
Dragee containing dry extracts of celandine 100 mg, turmeric rhizomes 45 mg, dandelion roots and leaves 10 mg. Used for cholecystopathy, as well as a means of additional therapy for hepatopathy.

23. Сholosom SL (Hevert, Germany)
A solution, 100 ml of which contains liquid extract of celandine (1: 1), made with 70% methanol - 40 g, liquid extract of turmeric rhizomes (1: 1), made with 60% ethanol - 20 g, and extract of herb and dandelion roots ( 1: 1), made on 30% ethanol - 20 g. It is used for cholecystopathy, flatulence and for parallel therapy of hepatopathies with feelings of nausea and bloating and related cardiac disorders.

24. Chol-truw S. (Truw, Germany)
Dragee containing dry extract of celandine 90 mg and dry extract of turmeric rhizomes 9.5 mg. It is used for mild spasms of the fundus of the stomach caused by disorders of the biliary tract.

25. Cynarzym N (Roland, Germany)
Dragee containing dry extracts of celandine 20 mg, artichoke 50 mg and boldo 30 mg. It is used for digestive disorders and enzymatic activity in liver diseases.

26. Esberigal N (Schaper & Brіmmer)
Dragee containing dry extracts of Benedictine knica herb 20 mg, milk thistle fruit 20 mg, celandine herb 40 mg and chamomile flowers 40 mg. It is used for inflammatory diseases and dysfunctions of the gallbladder, biliary tract and gastrointestinal tract.

27. Gallemolan forte (Redel, Germany)
Capsules containing dry extracts of dandelion roots and leaves - 20 mg and celandine herb 100 mg, standardized by the amount of alkaloids in terms of chelidonine - 2.1 mg. Used for dyspeptic disorders caused by functional disorders of the biliary tract.

28. Gallemolan G (Redel, Germany)
A solution containing a total liquid extract made in 44% alcohol from 2.4 g of bitter wormwood herb, 1 g of celandine herb, 2.4 g of boldo leaves, 2.4 g of chamomile flowers and 2.4 g of dandelion roots and herbs. Used for dyspeptic disorders caused by functional disorders of the biliary tract.

29. Gallopas tabl - / - tropfen (Pascoe, Germany)
Film-coated tablets and drops. The tablets contain a dry extract of celandine 118-211 mg, standardized by the amount of alkaloids 4 mg in terms of chelidonine. The drops contain a liquid extract of celandine herb, made ex tempore from 1 g of raw materials in a ratio (1: 1), which contains 1.2 mg of alkaloids in terms of chelidonine. Use for mild spasms of the biliary tract and gastrointestinal tract, cholecystitis and cholangitis.

30. Galloselect M (Dreluso, Germany)
Dragee containing 2.5 g of dry standardized extracts from celandine herb, dandelion roots and herb, milk thistle leaves, chamomile flowers and 0.5 mg of peppermint essential oil. Used for functional disorders of the biliary tract.

31. Hepar-Pasc (Pascoe, Germany)
Film-coated tablets containing 25 mg of methionine, dry extract of milk thistle fruit 47–53 mg and dry extract of celandine herb 18–27 mg, containing 2 mg of alkaloids in terms of chelidonine. It is used for acute and chronic liver diseases.

32. Hepaticum-medice N (Medice, Germany)
Tablets and pills containing crushed aloe leaves 70 mg, cinchona roots 20 mg, milk thistle fruit 25 mg, celandine herb 50 mg, gentian roots 25 mg, turmeric roots 70 mg. It is used for hepatocholecystopathy, flatulence, PCES, hepatogenic constipation, as well as adjuvant therapy for common acne, psoriasis and endogenous eczema.

33. Hepatimed N (Medice, Germany)
Film-coated tablets containing dry extracts of celandine herb 180-2000 mg, containing 4 mg of alkaloids in terms of chelidonine, milk thistle 81 mg, 35 mg of silymarin and turmeric 75 mg, active substance in terms of curcumin 40.5 mg ... It is used in the adjuvant therapy of cholecystocholangiopathies, acute and chronic cholecystitis, acne and constipation.

34. Hepatofalk planta (Falk Pharma Gmb, Germany)
Capsules containing dry extracts of milk thistle 132.1-162.8 mg, turmeric 25 mg and celandine 90-1000 mg, which contains 2.0-2.2% of the total alkaloids in terms of chelidonine. It is used for toxic liver damage and for maintenance therapy of chronic inflammatory liver diseases, cirrhosis of the liver and mild spasms of the biliary tract and gastrointestinal tract, as well as for dyspeptic disorders.

35. Hepatofalk Neu (Falk Pharma Gmb, Germany)
Dragee, a combined product consisting of synthetic dry plant extracts, including celandine extract. It is used for chronic hepatitis, cirrhosis of the liver, hepatosis, aging of the liver, treatment of the liver after acute hepatitis and overload, in the treatment of cholecystitis, cholangitis and biliary dyskinesia.

36. Heumann Leber - und Gallen Te Solu - Hepar NT (Heumann, Germany)
Powder, packaged in 2 g, or powder in a bag, a tablespoon of which contains dry extract of boldo leaves (6.5: 1) 60 mg, dry extract of celandine herb (6: 1) 68 mg and peppermint essential oil 4 mg. Used for hepatoprotective therapy of diseases of the biliary tract.

37. Hevert Gall S (Hevert, Germany)
Fruit juice with plant extracts, which contains alcoholic celandine herb extract (1: 1) 0.5 ml, extract of herb Benedictine Benedictine herb alcohol (1: 1) 0.8 ml, chamomile flower extract liquid 1.5 ml, herb extract dandelion alcohol (1: 1) 1 ml, essential oil of caraway seeds 0.05 ml, essential oil of peppermint leaves 0.02 ml, tincture of boldo leaves (1: 5) 2.5 ml, tincture of calamus rhizomes 0.8 ml, tincture of milk thistle leaves 0.6 ml, tincture of turmeric rhizomes (1: 5) 2 ml. They are used for diseases of the liver, biliary tract and duodenum 12.

38. Hevert Magen-Galle-Leber-Tee (Hevert, Germany)

Healing tea of 10 types of medicinal raw materials, 100 g of which contain calendula inflorescences 2 g, fennel fruits 20 g, wormwood herb 10 g, centaury herb 5 g, celandine herb 2 g, chicory herb 38 g, yarrow herb 10 g, thyme herb 5 g, calamus rhizomes 8 g. It is used in the form of a water decoction (tea) for gastritis, cholecystitis, a feeling of fullness in the stomach and as an adjuvant therapy for stomach ulcers.

39. Horvila N (Schхning-Berlin, Germany)
Dragee containing dry extract (6.7: 1) of turmeric rhizomes (6.7: 1) 25.9 mg, dry extract of celandine herb (6.7: 1) 60-90 mg, which consists of the sum of alkaloids in terms of chelidonine 2 mg and peppermint essential oil 20 mg. It is used in adjuvant therapy for non-inflammatory diseases of the gallbladder, gastric diseases caused by digestive disorders.

40. Iberogast Tinctur (Stegenwald, Germany)
Tincture, 100 ml of which contains alcoholic extracts of angelica rhizomes (3.5: 10) 10 ml, Chinese tea leaves (3.5: 10) 20 ml, 10 types of medicinal raw materials, including celandine herb. It is used for functional and motor disorders of the stomach and intestines, gastritis, gastrointestinal spasms, stomach and duodenal ulcers.

41. Infi-Tract-N (Infi rmarius-rovit, Germany)
Drops containing extracts of 10 types of medicinal raw materials, including celandine herb mixed with ascorbic acid. It is used to stimulate bile secretion, in case of indigestion and motor function of the gallbladder, spasms that occur in case of indigestion.

42. Jucholan S (Jukunda, Germany)
Drops, 10 ml of which contain extracts prepared in 45% alcohol from 11.6 g of milk thistle seeds, 2 g of St. John's wort, 1.2 g of dandelion roots and herbs, 1.2 g of celandine herb and 0.8 g of peppermint. They are used for diseases of the liver, gallbladder and biliary tract.

43. Legapas comp (Pascoe, Germany)
Drops containing a liquid extract (1: 1.0-1.2) of cascara bark 500 mg, 20 mg in terms of cascaroside A, milk thistle fruit 4 mg, which contains 40 mg of silymarin, celandine herb 3 mg, which contains 2.5 mg of alkaloids in terms of chelidonine, and liquid extract (1:08) of dandelion. They are used for hepatopathies with a predominance of constipation with obstructed outflow of bile, and also as a choleretic agent.

44. Marianon DrKlein (Klein, Germany)
Drops containing extracts of celandine, wormwood, yarrow and St. John's wort. Used for cholecystopathy, cholelithiasis, cholangitis and biliary dyskinesia.

45. Marienbader Pillen (Palmicol, Germany)
Dragee containing dry extract of celandine (8: 1) in 70% methanol 0.035 g, dry aloe cape juice 0.02 g, sea salt 0.028 g and phenolphthalein 0.05 g. Used for acute and chronic constipation.

46. Neurochol C (Kytta-Siegfried, Germany)
Dragee containing dry extract of celandine herb (5: 1-10: 1), made on 70% methanol 132-138 mg, standardized by the content of the sum of alkaloids, which is not less than 4.6 mg in terms of chelidonine; dry extract of herb with dandelion roots 75.2 mg and dry extract of herb bitter wormwood 30.4 mg. They are used for dyspeptic disorders, especially for functional disorders of the excretory biliary system.

47. Nervogastrol (Heumann)
Tablets containing bismuth nitrate; 12 mg, turmeric rhizome extract (6: 1) 30 mg. It is used for mild cramps in the supra-gastric region caused by functional disorders of the biliary tract.

48. Panchelidon N (Kanold, Germany)
Capsules and drops on 70% methanol, 200 mg of which contain 4.4 mg of the total alkaloids in terms of chelidonine. The drops contain a liquid extract of celandine herb, standardized by the amount of alkaloids, 0.4% in terms of chelidonine. Used for mild spasms of the biliary tract and gastrointestinal tract.

49. Pascohepan novo (Pascoe, Germany)
Drops, 1 g of which contains liquid extract of milk thistle fruit (1–0.8: 1.2) 400 mg; liquid extract of celandine herb 300 mg, which contains 3.6 mg of alkaloids in terms of chelidonine, and liquid extract of dandelion roots (1: 1) 300 mg. They are used for hepatopathies and insufficient bile secretion.

50. Paverysat forteBurgen (Ysatfabrik, Germany)
Drops containing a dry aqueous-alcoholic extract of celandine (6.7: 1) 25 ml, standardized by the amount of alkaloids 500 mg in terms of chelidonine and a tincture of turmeric roots (1: 10.40) 5 g, standardized by the content of curcumin 200 mg. It is used for mild cramps in the supra-gastric region caused by functional disorders of the excretory system and biliary tract.

51. Presselin Hepaticum P Leber-Galle-tabletten (Presselin, Germany)
Tablets containing the amount of dried and crushed roots and dandelion herb 20 mg, celandine herb 80 mg and milk thistle fruit 175 mg. It is used for functional disorders and inflammation of the gallbladder, biliary tract, liver, feeling of fullness in the stomach, bloating and heart disorders caused by the above diseases.

52.Schwаheran (Pharma Schwaher, Germany)
Dragee containing dry extract of milk thistle fruit 125 mg, dry extract of celandine herb 170 mg, standardized by the amount of alkaloids 3.4–3.7 mg in terms of chelidonine. It is used for toxic liver damage, chronic and inflammatory liver diseases, mild convulsions of the biliary tract and gastrointestinal tract.

53. Silugital-Tropfen (Вio-ce-be, Germany)
Drops containing aqueous-alcoholic extracts-percolates of celandine herb 10 ml, which contains 10 mg of the total alkaloids in terms of chelidonine, and milk thistle fruits 50 ml with the amount of extracts made in 40% alcohol in the ratio of raw materials: extractant 1: 1 from yarrow herb 10 g, bitter wormwood herb 5 g, turmeric herb 5 g. It is used for hepatopathies and cholecystopathies of the same genesis and biliary dyskinesia.

54. Spasmo gallo sanat (Sanol, Germany)
Dragee containing dry extract of celandine and turmeric rhizomes. They are used for mild spasms of the biliary tract and gastrointestinal tract, chronic disorders in the supra-gastric region and functional disorders of the excretory and biliary tract.

55. Spasmo-CC-Steiner (Steiner, Germany)
Granules containing dry extracts of celandine and turmeric. They are used for mild spasms of the supragastric region caused by functional disorders of the biliary system.

56. Steigal Filmtabletten / Fluidextract (Steigerwald, Germany)
Film-coated tablets and liquid extract containing dry extracts of celandine and turmeric. The liquid extract is used for mild spasms of the supragastric region caused by functional disorders of the biliary tract.

57. Ukrain (Nowicky Pharma, Austria)
5 ml ampoules containing 5 mg of thiophosphate derivatives of alkaloids isolated from celandine. It is prescribed for malignant neoplasms, in particular for adenocarcinoma of the rectum, cancer of the breast and bladder, prostate, testicles, cervix, squamous cell epithelial cancer, lung cancer, sarcoma, melanoma, lymphoma. The drug is administered intravenously or intramuscularly, starting with a dose of 5 mg, once a day, 5 mg daily, increasing the dose by 5 mg to a maximum dose of 20 mg. The usual regimen of drug use: 2 times a week for 5 weeks with a break of 1-2 weeks. In the future, 6 more courses are carried out for 5 weeks with intervals of 2-4 months. For brain tumors, the drug is used with great caution, only in stationary conditions due to possible reversible tumor edema. Should not be administered concurrently with glucocorticosteroids or other immunosuppressants, since they neutralize the immunostimulating effect of the drug. Efficiency in advanced forms of cancer is insufficient, but there is an improvement in the quality of life of patients. Contraindications for use: pregnancy, except for cases of malignant tumor of the fetus, lactation, severe fever.

Photos and illustrations:

Herb botanical description photo pharmacognosy family medicinal properties application fruit raw material

Latin name Chelidonium majus L.

Description

Celandine is great. Teberda reserve.

Perennial herb of the poppy family up to 90 cm high.

Taproot, slightly branched. Rhizome multi-headed, short.

The stem is straight, hollow, ribbed, densely branched, covered with hairs, at the break it secretes a yellowish-orange juice.

The leaves are pinnate, alternate, crenate, pinnately dissected, light green above, gray below. The lower leaves are on long petioles, the upper ones are sessile.

Flowers on thin, long stalks, yellow, collected in umbellate inflorescences.

The fruit is a pod capsule.

Blooms in May - August. Ripens in July - September.

Spreading

Distributed in most of the European territory of the USSR, in the Caucasus, in Kazakhstan and Central Asia. It grows in shady places near dwellings, in vegetable gardens, forests, in fields, in felling areas, burnt-out areas, on the slopes and talus of mountains.

Teberda Nature Reserve. In deciduous forests, among shrubs, in weedy places in the forest belt, 1300-1350 m above sea level. Usually.

Chemical composition

Active ingredients

The aerial part contains organic acids (citric, succinic, malic), essential oil, saponins, alkaloids (coptisins, protopin, chelidonin, cheleritin, sanguinarine, etc.), choline, histamine, tyramine, methylalanine, vitamin C, provitamin A, carotene, flavonoids , tannins and phenol carboxylic acids.

Celandine great Application

The aerial part of the plant is used to dye the wool yellow. For various mordants, celandine gives a range of shades of yellow. In veterinary medicine, it is used to treat bloody urine in cattle and ringworm in dogs. In gardens and vegetable gardens, it is used as an insecticide against pests.

Raw materials

Stems, leaves, flowers and roots have healing properties. The grass is harvested in May - June in the flowering phase in dry weather, cutting or breaking off branches at a height of 10-15 cm from the ground., Roots - in the fall. Dried in the attic or under a canopy with good ventilation or in a dryer at a temperature of 50 ... 60 ° C, spreading out in a thin layer. When bent, the finished raw material breaks, not bends. Store in bags or wooden containers for 3 years.

Medicinal use

Celandine is known for its antiseptic properties, it is used mainly for the treatment of skin diseases - corns, warts. Recently it became known that the infusion of celandine is able to delay the growth of malignant tumors.

Celandine preparations have anti-inflammatory, antipruritic, antimicrobial, wound healing, analgesic, antihistamine, diuretic, choleretic, anticonvulsant and cauterizing effects. They significantly reduce or prevent the development of certain fungal diseases, have antiviral effect.

Plants use fresh juice and finely ground grass to remove warts, corns, freckles. They are cauterized with condylomas, treated with lupus erythematosus, periodontal disease, rectal polyps, psoriasis, eczema and furunculosis. Fresh juice and chopped grass are applied to the affected areas of the skin or apply compresses. The procedure is repeated 3 times a day.

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